{"id":14036,"date":"2026-07-09T13:13:46","date_gmt":"2026-07-09T09:13:46","guid":{"rendered":"https:\/\/www.medest.am\/blog\/pdrn-injection\/"},"modified":"2026-07-09T13:55:12","modified_gmt":"2026-07-09T09:55:12","slug":"pdrn-injection","status":"publish","type":"reason","link":"https:\/\/www.medest.am\/en\/blog\/pdrn-injection\/","title":{"rendered":"Polynucleotides for the Face: What They Are and How These PDRN Injections Work"},"content":{"rendered":"\n<p>If you&#8217;ve heard about polynucleotides but aren&#8217;t sure how they differ from traditional skin biorevitalization, this article will help you understand.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What Are Polynucleotides?<\/strong><\/h2>\n\n\n\n<p>Polynucleotides (PDRN) are DNA fragments derived from salmon. Their molecular structure is highly similar to human DNA, allowing them to effectively stimulate the skin&#8217;s natural regeneration processes while being well tolerated by the body.<\/p>\n\n\n\n<p>It&#8217;s important to understand that polynucleotides are <strong>not<\/strong> dermal fillers or conventional hydrating treatments. While hyaluronic acid works primarily in the extracellular space by retaining moisture and providing temporary volume, PDRN penetrates deeper into the skin, supporting cellular regeneration from within.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/www.medest.am\/wp-content\/uploads\/\/dded5246-fb6f-420a-9b84-8a88be932159-1024x667.png\" alt=\"PDRN \u0438\u043d\u044a\u0435\u043a\u0446\u0438\u0438 \u0432 \u043a\u043b\u0438\u043d\u0438\u043a\u0435 \u041c\u0435\u0434\u0435\u0441\u0442 \u0415\u0440\u0435\u0432\u0430\u043d\" class=\"wp-image-14024\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How Does the Procedure Work?<\/strong><\/h2>\n\n\n\n<p>Once injected into the skin, polynucleotides act as biostimulators. They activate skin cells and promote the production of collagen and elastin, helping to improve skin quality over time.<\/p>\n\n\n\n<p>The results are gradual rather than immediate. Improvements develop throughout the treatment course and continue for several weeks after the final session.<\/p>\n\n\n\n<p>A typical treatment plan includes <strong>2\u20134 sessions<\/strong> spaced <strong>2\u20134 weeks apart<\/strong>. Results generally last <strong>6\u201312 months<\/strong>, with maintenance treatments recommended every <strong>3\u20136 months<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>What Results Can You Expect?<\/strong><\/h2>\n\n\n\n<p>The outcome is subtle, natural-looking, and focused on improving skin quality rather than changing facial features. The skin appears healthier, smoother, more radiant, and more even in both texture and tone.<\/p>\n\n\n\n<p>Unlike dermal fillers or neuromodulators, polynucleotides do not add volume, alter facial contours, or affect facial expressions. Instead, they support the skin&#8217;s own regenerative processes, resulting in gradual, natural rejuvenation.<\/p>\n\n\n\n<p>Polynucleotide treatments are commonly recommended for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Dull, tired-looking skin<\/li>\n\n\n\n<li>Loss of firmness and elasticity<\/li>\n\n\n\n<li>Fine lines<\/li>\n\n\n\n<li>Post-acne marks<\/li>\n\n\n\n<li>Dehydrated skin<\/li>\n\n\n\n<li>Early signs of skin aging<\/li>\n\n\n\n<li>Preventive anti-aging care<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Recovery After Treatment<\/strong><\/h2>\n\n\n\n<p>Recovery is minimal. Small injection bumps (papules) may appear immediately after treatment and usually resolve within <strong>1\u20132 days<\/strong>. Bruising is uncommon and, if it occurs, typically disappears within <strong>3\u20135 days<\/strong>.<\/p>\n\n\n\n<p>For several days after the procedure, patients are advised to avoid direct sun exposure, saunas, steam rooms, and intense physical exercise.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Is This Treatment Right for You?<\/strong><\/h2>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>If you&#8217;re considering polynucleotide injections and would like to know whether they&#8217;re suitable for your skin, schedule a consultation with a <strong>Medest<\/strong> cosmetic physician. After assessing your skin&#8217;s condition and discussing your goals, your specialist will recommend a personalized treatment plan tailored to your needs.<\/p>\n<\/blockquote>\n\n\n\n<p><\/p>\n","protected":false},"featured_media":14031,"template":"","service_cat":[],"reason_cat":[],"class_list":["post-14036","reason","type-reason","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/reason\/14036","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/reason"}],"about":[{"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/types\/reason"}],"version-history":[{"count":2,"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/reason\/14036\/revisions"}],"predecessor-version":[{"id":14043,"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/reason\/14036\/revisions\/14043"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/media\/14031"}],"wp:attachment":[{"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/media?parent=14036"}],"wp:term":[{"taxonomy":"service_cat","embeddable":true,"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/service_cat?post=14036"},{"taxonomy":"reason_cat","embeddable":true,"href":"https:\/\/www.medest.am\/en\/wp-json\/wp\/v2\/reason_cat?post=14036"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}